The gene has been repeatedly detected, often together with the neighbor ASIP gene, in association studies concerning skin pigmentation and skin neoplasms, (https://www.ncbi.nlm.nih.gov/gap/phegeni?tab=1&amp;gene=22913; Jacobs et al., 2015), as well as in several other type of cancers, where it is considered to represent a metastatic marker (Roberts et al., 2019). This evidence concerns the gene ASIP and cancer.