MYO7A and Usher syndrome: Also, it has been shown to co-localize with the three proteins, transmembrane (Cdh23), scaffold (harmonin), and actin-based motor (Myo7a), whose defect is responsible of various types of the Usher syndrome, a multi-genic congenital disease characterized by perturbation of normal organization and growth of hair bundles within the inner ear (Blanco-Sánchez et al., 2014)