Of these, three hub genes involving angiotensin II receptor, type 2 (AGTR2), fibroblast growth factor 13 (FGF13), and lysophosphatidic acid (LPA) receptor 3 (LPAR3) (Figure 5B, marked by red color) have been reported to participate in cell migration and angiogenesis in bladder cancer or lactotroph tumors (Pei et al., 2017; Wierinckx et al., 2018; Chen et al., 2019). The gene discussed is LPAR3; the disease is urinary bladder cancer.