A recent study in which transcriptional analysis of the infected muscle tissue of mice was performed by RNA sequencing showed that a number of inflammation-associated genes were upregulated in regions of myonecrosis induced by C. perfringens (Low et al., 2018), including genes of the chemokine family CXCL2, and of proinflammatory cytokines such as IL-1β and IL-6. The gene discussed is IL1B; the disease is gas gangrene.