Results showed that lentiviral-coated CKS1 was transfected into HCT116 cells successfully (Fig. 3a), and this CKS1-expressing HCT116 cells can significantly promote tumor growth in vivo (Fig. 3b, c), these larger tumor tissues obtained from experiment group has a high expression level of CKS1 than tissues obtained from control group (Fig. 3d). Here, CKS1B is linked to neoplasm.