GPC3 and hepatocellular carcinoma: Using the MCT4+/GPC3+ HCC cases, except for one case showing mixed reciprocal and synergistic interactions of MCT4 and GPC3 (total 43 cases), we statistically analyzed the correlation between clinicopathological variables of the reciprocal HCC cases (29 cases) and those of the non-reciprocal ones (synergistic cases + irrelevant cases; 14 cases in total) (Table 1).