The immunolocalization pattern of GPC3 in HCC showing the reciprocal interaction with MCT4 was circumferential membranous (5 cases), circumferential membranous and cytoplasmic (8), circumferential/canalicular membranous and cytoplasmic (5), canalicular membranous and cytoplasmic (1), or cytoplasmic (10). Here, GPC3 is linked to hepatocellular carcinoma.