As reported in our previous studies [2, 4], we designated MCT4-positive HCC (MCT4+ HCC) and GPC3-positive HCC (GPC3+ HCC) as HCC cells with readily recognizable membranous MCT4 expression and HCC cells with readily recognizable membranous (circumferential, canalicular, and luminal) and/or cytoplasmic GPC3 expression, respectively. This evidence concerns the gene GPC3 and hepatocellular carcinoma.