Based on the log-rank test in GEPIA, abundant mRNA expression of DUOX1 (hazard ratio 0.45, 95% confidence interval, p = 0.00082) and NOX2 (hazard ratio 0.63, 95% confidence interval, p = 0.049) was significantly associated with better prognosis of CESC patients in terms of overall survival (Fig. 2a). The gene discussed is DUOX1; the disease is cervical squamous cell carcinoma.