SYCN and pachyonychia congenita: Finally, a set of robust prognostic signatures including SYCN, PNLIPRP1, CAP2, GNMT, MAT1A, ABAT, GPT2, ADHFE1, PHGDH, PSAT1, ERP27, PDIA2, MT1H, COMP, COL5A2, FN1, COL1A2, FAP and POSTN were identified by lasso regression analysis from DEGs and could diagnose the PC.