EGFR and glioblastoma: According to the 2016 World Health Organization (WHO) classification of central nervous system tumors, glioblastomas can be divided into a series molecular subtype based on IDH (isocitrate dehydrogenase) mutation, EGFR (epidermal growth factor receptor) status, alterations in TP53, methylation of MGMT, 1p19q co-deletion and etc [2, 3].