CPSF4 and glioblastoma: As ZIKV-infection could trigger neurological defects in children born from infected women5,9,40, the in vitro anti-ZIKV activity of NAR was assessed in cell lines potentially involved in ZIKV-pathogenesis, like human glioblastoma cell line (A172) and human embryonic stem cell line (NKX2-5eGFP/whESC).