Strikingly, the double transgenic (Tg-Neu;EZH2T416D) mammary tumor tissues remained CK14-positive and CK18-negative (Fig. 1c, third panels), which were phenotypically similar to the basal-like mammary tumor tissues from Tg-C3T21 control mice (Fig. 1c, bottom panels). The gene discussed is KRT14; the disease is breast cancer.