We further examined nine tumors from different Tg-Neu;EZH2T416D mice by IHC staining with results indicating that 78% of the tumors were strong CK14 positive and CK18 negative, and only 22% were CK18 positive (among them, one tumor displayed bi-lineage: CK18/CK14 double positive). Here, ERBB2 is linked to neoplasm.