INS and hydrops fetalis: Somewhat in line with the results for the IP-GTT when comparing between HFC and LFC, the IP-ITT revealed a significant effect of HF diet on blood glucose levels at 0 (t12 = 2.930 p < 0.05) and 15 (t12 = 5.550 p < 0.001) minutes post-insulin challenge, compared with the LFC (Fig. 2G).