ITGAE and neoplasm: As opposed to IR alone, which led to an increase only in the irradiated lung, IR plus inhalation induced significantly upregulated antigen presentation on CD103+ DCs in both lungs (Fig. 4c), and the CD103+ DCs with high antigen presentation were also detected in TDLNs (Fig. 4d), implicating migration of these APCs from tumor sites to TDLNs where they cross-prime T cells.