Consistent with tuberoinfundibular dopaminergic neurons remaining unaffected in individuals with PD (Braak et al., 2003; Langston and Forno, 1978), the ME in MPTP-dosed mice shows rapid reversal (within 24 h) of TH and dopamine loss (Benskey et al., 2012; Benskey et al., 2013). Here, TH is linked to Parkinson disease.