Miki Nakamura et al. demonstrated that CAM augmented the antitumor activity of thalidomide against multiple myeloma (MM) cells through autophagy attenuation [7], and it has been reported that CAM enhanced bortezomib-induced cytotoxicity via ER stress-mediated CHOP induction in breast cancer cells [8]. The gene discussed is DDIT3; the disease is AL amyloidosis.