Based on previous studies, the principal mechanisms of anti-tumor activity are involved in pro-inflammatory cytokines or chemokines reduction [6], autophage attenuation [7], endoplasmic reticulum stress-mediated C/EBP homologous protein (CHOP) induction [8], anti-angiogenesis [9], nuclear transcription factors and reactive oxygen species et al. [10]. Here, DDIT3 is linked to neoplasm.