GINS2 and central nervous system cancer: Recent years, some studies have found that GINS2 is a novel prognostic biomarker and promoted tumor progression in early-stage cervical cancer [38]; GINS2 is closely related to the occurrence and development of glioma, and may become a prognostic marker for glioma patients [39]; GINS2 is markedly expressed in EOC tissues and cell lines, stable GINS2 knockdown in SKOV-3 cells could significantly inhibit cell proliferation and induce cell cycle arrest and cell apoptosis [40].