RAB27A and neoplasm: For example, some studies have indicated that over-expression of miR-182 shows increased tumour cell growth and proliferation, highly aggressive features, and tumor progression through repression of a plethora of targets (e.g., CAMK2N1 [9], RAB27A [10] and activation of Wnt/β-catenin signal pathway [11]; Perilli et al. [12] have found that circulating miR-182 can serve as a biomarker for tumor progression.