ZEB1 and non-small cell lung carcinoma: Although the presence of Zeb1 mRNA has been also described in exosomes derived from mesenchymal non-small cell lung cancer cells [34], this is the first time the enrichment of this transcription factor in HPASMC-EVs has been demonstrated and puts these EVs in the spotlight as potential contributors for EndoMT, thus they might play an important role in vascular remodelling occurring during development.