Important signatures of a variety of immune cells including CD8 + T cells, T cells (general), B cells, monocytes, tumor-associated macrophages, M1 macrophages, M2 macrophages, neutrophils, natural killer cells, dendritic cells, Th1, Th2, Tfh, Th17, regulatory T cells (Treg), T cell exhaustion are illustrated in Additional file 3: Table S4. Here, CD8A is linked to neoplasm.