SMAD2 and hepatocellular carcinoma: Additionally, suppression of integrin β1 resulted in an increase of miRNA-24-3p (Fig. 5h) and a decrease of Furin, TGF β1, Smad2/3 phosphorylation, and Snail in HCC cells grown on higher stiffness substrate (Fig. 5i), but inhibition of miRNA-24-3p reversed the above corresponding changes (Fig. 5j).