Other components of CENPA-NAC, including CENPA, CENPF, and CENPH, were all described to be correlated with tumors, for example, overexpression and mistargeting of CENP-A could contribute to human primary colorectal cancer [17], CENPF had been linked to a poor prognosis in breast cancer, colorectal gastrointestinal stromal tumors and nasopharyngeal carcinoma patients [19]. The gene discussed is CENPA; the disease is colorectal cancer.