Bradykinin is involved in regulation of multiple physiological processes, including ovulation, oocyte maturation, prostaglandin production [86], vasodilation [87], diuresis [88] etc. Bradykinin is also involved in several pathological states, one of the most prominent being cancer, where bradykinin is considered among the key players that contributes to cell proliferation, migration, invasion, and tumor growth [89]. Here, KNG1 is linked to neoplasm.