Indeed, stonin 2 was upregulated in multiple ovarian cancer cell lines (CAOV3, COV362, COV504, EFO-27, A2780, OVCAR4, SKOV3, and TOV-21G) compared to non-tumorigenic human ovarian surface epithelial cells (HOSEpiC), and in ovarian cancer tissue samples compared to control conditions [80]. This evidence concerns the gene STON2 and ovarian carcinoma.