H1 is expressed in multiples types of cancer, including ovarian cancer, and its role in cancer prognosis might be related to the fact that the promoter region of H1 gene contains the binding sites for glucocorticoid receptor (GR), signal transducer and activator of transcription 5A (STAT5A), and c-Myb regulatory transcription factor [106]. This evidence concerns the gene NR3C1 and ovarian cancer.