IGHE and coronary artery disorder: They found a significantly increased ischemic heart disease risk (relative risk (RR) = 3.4; 95% CI: 1.4–8.4) and non-fatal AMI development (RR = 7.3; 95% CI: 2.2–23.9) in males with baseline IgE levels of ≥200 kU/L compared with those with low baseline IgE levels) [12].