DCK and hepatocellular carcinoma: Figure 3a,b shows a higher dCK expression in HCC than the surrounding liver tissues from both human (RNA-seq) and woodchuck (microarray) results. PCR with harvested woodchuck liver tissues using the woodchuck-specific primer for dCK verified the higher expression of dCK in HCC (Figure 3c). Inversely, PNP showed a higher expression, in terms of the base main count in either RNA-seq (human) or microarray (woodchuck) data, in the liver parenchyma than in HCC (Figure S1 in Supplementary Materials) for human and woodchuck, with a 92% homology between the two species.