LLGL1 and acute myeloid leukemia: Reduced LLGL1 expression was associated with significantly decreased OS patients [52], while high expression of PTK7 by flow cytometry in AML correlated with core-binding factor aberrations (t(8;21), inv(16); 19/20 cases) and was also common in AML with 5q- and -7 (21/24 patients) or in cases with normal karyotype (56/65 patients), so in low, intermediate and high cytogenetic risk groups.