SOX2 and nasopharyngeal carcinoma: In recent years, reports have revealed that aberrant expression of lncRNAs can modulate cell proliferation and migration in various tumors.20 The implication of lncRNAs in NPC, a common malignancy with high death rate, has also been demonstrated.21 For instance, DANCR plays a metastasis‐promoting role in NPC.22 ANRIL activated by SOX2 facilitates cell growth in NPC.23 NEAT1 affects NPC cell migration through targeting miR‐101‐3p.24 In this study, we investigated a novel lncRNA LINC01116 in the development of NPC.