KLRK1 and neoplasm: Especially the killing of target cells by NK cells depends on a balance of various activating and inhibitory receptors, and the expression of the stress‐induced ligands for NKG2D by tumor cells results in their lysis.34 We found that activated T and NK cells in BRAFi‐sensitive tumors had a higher expression of NKG2D that was abrogated by resistance development.