For instance, CERS6 serves as an oncogene to promote the progression of gastric cancer through the SOCS2/JAK2/STAT3 signaling pathway.27 It is also reported that elevated CERS6 expression was associated with increased invasion of lung cancer cells and poor prognosis,28 while the function of CERS6 in BC remain unclear. The gene discussed is STAT3; the disease is lung carcinoma.