Both cell lines have been used in the IL‐1 field for decades (Saklatvala et al, 1991; Bird et al, 1994; Freshney et al, 1994; Guesdon et al, 1997) and were originally isolated as separate epithelial carcinoma cell lines (Eagle, 1955a,b), but KB cells were later found to be a derivative of HeLa (Vaughan et al, 2017). This evidence concerns the gene IL1A and carcinoma.