Furthermore, there are premises suggesting value of some biomarkers in the diagnosis of specific stroke types, such as cardioembolic stroke (vWF, TNFα), hemorrhagic stroke (GFAP, MMP-9), large- and small-artery disease (IL-6; TNFα), or lacunar stroke (Glu, GABA) [3, 66, 217, 221]. This evidence concerns the gene MMP9 and Stroke.