Although C5b-9 and FHR5 staining intensities were greater in the biopsy with glomerular inflammation, the detection of C5b-9 and FHR5 in a potential kidney donor with normal renal function but subclinical CFHR5 nephropathy shows that glomerular complement deposition can be detected in the absence of glomerular inflammation in CFHR5 nephropathy. This evidence concerns the gene CFHR5 and kidney disorder.