APC and neoplasm: γδ T cells are known to have dual effects, capable of exerting both pro-tumor or antitumor response depending on their subtype.31 γδT1, γδT-APC, and γδTfh subtypes all possess antitumor activities such as secreting chemoattracting chemokines (i.e., CXLC13), antigen presentation, and antibody-dependent cell-mediated cytotoxicity toward cancer cells.32 In breast cancer, MCs are linked with pro-angiogenic factors such as inflammation33,34 reflecting a higher MC count in the predicted high-risk group.