IFNG and breast cancer: Among breast cancers (n = 944), the most common immunogenomic subtypes identified were IFN-γ dominant, followed by wound healing, and inflammatory (Fig. 1).1 Sixty percent of basal-like breast cancers were of the IFN-γ dominant subtype and a little less than half of HER2-enriched (HER2+) and luminal B breast cancers were of the IFN-γ dominant subtype.