The telomerase activity is also a kind of RTase responsible for the elongation or maintenance of telomere sequence repeat to the 3′ end of telomeres using telomerase RNA component (TERC) and the high level of telomerase activity was expressed in the immortal cell lines, such as cancers and embryonic stem cells (Weinrich et al. 1997; Artandi and DePinho 2010; Kim et al. 2017). This evidence concerns the gene TERC and cancer.