ANXA5 and acute myeloid leukemia: MTT assays and standard isobologram analyses revealed substantial synergy between CX-5461 and AZD6738 in 10 primary AML patient samples ex vivo (Fig. S5b), which was further confirmed via Annexin V/PI staining and flow cytometry analyses of primary samples from three AML patients for whom adequate blasts were available (Fig. 1j).