VEGFC and myocardial infarction: To further elucidate the mechanism by which VEGF-C-induced lymphangiogenesis improves cardiac function after MI, in a follow-up study, the authors documented a significant influx of circulating monocytes and activated macrophages that undertake extensive phagocytic activity in the infarcted region after MI; these immune cells in the injured heart are dependent on lymphatic vessels to circulate back to the lymph nodes37.