Based on previous data in murine models that have shown that miR-146a modulates IL-6 and IL-10 production in response to LPS, the effects of miR-146a inhibition on the production of IL-6, IL-10 and IL-8 were compared in CF macrophages transfected with the miR-146a inhibitor16,26. This evidence concerns the gene IL10 and cystic fibrosis.