Allopurinol which commonly used to treat gout and specific types of kidney stones, also induces SCARs, including SJS/TEN, and allopurinol-induced SCARs are previously reported to be strongly associated with HLA-B* 58:01 in Han Chinese10, Caucasian11, and Japanese patients12. The gene discussed is HLA-B; the disease is Schwartz-Jampel syndrome.