These included survivin, an apoptotic and mitotic regulator, that is overexpressed in melanoma and promotes melanoma metastasis9, matrix metalloproteins (MMPs), proteases that facilitate invasion, metastasis and regulate tumor cell proliferation and apoptosis10, and Bcl-2 (B-cell lymphoma 2), another regulator of apoptosis11. Here, BIRC5 is linked to melanoma.