INS and Familial prostate cancer: These enriched KEGG pathways annotations were (1) “PPAR signaling pathway” (P = 1.28e−14), (2) “adipocytokine signaling pathway” (P = 3.87e−13), (3) “pathways in cancer” (P = 1.10e−09), (4) “insulin signaling pathway” (P = 4.39e−09), (5) “prostate cancer” (P = 1.89e−07), and (6) “type II diabetes mellitus” (P = 2.15e−07).