CCL5 and Zika virus infectious disease: HBCA infection with another flavivirus, Zika virus, is associated with only limited activation of immune cytokine/chemokine response, but ZIKV infection induces the highest upregulation of CXCL10, IL-6, 8, 12, and CCL5 (RANTES) [55], which corresponds with the observations in TBEV-infected HBCA.