GPX1 and breast cancer: Regarding GPx1, the antioxidant effect of this enzyme is of paramount importance in cancer treatment, given that reactive oxygen species (ROS) promote cancer progression, as has been demonstrated by decreased tumor recurrence and metastasis markers by ROS scavenging [40,41], as well as by the induction of cancer cells death and tumor shrinkage by GPx1 overexpression and curcumin administration in breast cancer and lymphoma [37,42,43].