Previous studies also showed that cancer cells can evade natural killer T‐like and natural killer cells cytotoxic attack by affecting the production of granzyme B.60 We have previously shown that granzyme B promotes CTL transmigration,61 thus the production of granzyme and perforin in Arp3‐KD cells with the transmigration would warrant further investigation. The gene discussed is PRF1; the disease is cancer.