LBR and infection: C. psittaci SinC displays two properties that are unprecedented for Chlamydia effector proteins: (1) after secretion at late stages of infection, SinC localizes to the inner nuclear membrane of the infected cell, where it associates with LEM domain proteins, including emerin and the lamin B receptor (LBR), and (2) SinC enters into neighboring, uninfected cells, in which it also localizes to the nuclear membrane [18].