As predicted, DSS‐induced colitis in Card9−/−‐ mice inhibited intestinal epithelial restoration and impaired gut recovery by significantly increasing apoptosis and reducing proliferation of intestinal epithelial cells.4 Given the impaired immune responses and injured intestinal epithelial cells, Card9‐null mice were less efficient in controlling fungal colonization, increasing their susceptibility to intestinal inflammation.3, 4. The gene discussed is CARD9; the disease is colitis.