Low CXCR3 expression was not significantly associated with age, gender, tumor region, surgery type, progression, and metastasis, but was correlated with tumor site (femur vs. tibia: OR = 3.1, 95% CI = 1.02–9.37, P=0.046) and histologic response (poor vs. good: OR = 4.2, 95% CI = 1.21–14.54, P=0.024). The gene discussed is CXCR3; the disease is neoplasm.