AFAP1 and non-small cell lung carcinoma: It was found that the drug-induced growth inhibition increased in a dose-dependent manner, and AFAP1-AS1 knockdown increased the inhibitory activity of DDP and 5-FU in NSCLC cells (Figures 4A–D), implying that suppression of AFAP1-AS1 alleviated the chemotherapy resistance of NSCLC cells.