The downstream binding targets of miR-338-3p, including N-cadherin (Chen et al., 2017), MACC1 (Zhang et al., 2016b), HIF-1α (Xu et al., 2014), and CyclinD1 (Fu et al., 2012) have also been well studied in HCC. This evidence concerns the gene MACC1 and hepatocellular carcinoma.