Serum ALCAM proved to have comparable diagnostic power to PSA, performing slightly better at identifying those patients who died of PRCa (ALCAM AUC = 0.80, 95% CI 0.69 – 0.91 compared to PSA AUC = 0.71, 95% CI 0.51 – 0.91) (Figure 2G) and slightly worse at identifying those patients with metastasis (ALCAM AUC = 0.88, 95% CI 0.78 – 0.99 vs. PSA AUC = 0.95, 95% CI 0.88 – 1.02) (Figure 2H). The gene discussed is ALCAM; the disease is pure red-cell aplasia.