CD274 and non-small cell lung carcinoma: AZD4635 as a mono-agent or combined with durvalumab (ant-PD-L1) is being investigated for the therapy of patients with advanced solid malignancies, NSCLC, metastatic castrate-resistant prostate carcinoma (mCRPC), and colorectal carcinoma (CC) (NCT02740985), but it has not been completed until now.