HOXA11 and gastric cancer: Moreover, CK636, the small molecule inhibitor of Arp2/3 complex which has been confirmed to participate in the process by which HOXA11 regulates the migration and invasion of gastric cancer cells, could also downregulate the expression of Arpc2 and Arpc3 which were upregulated by HOXA11 (Figure 6C and Figure S2C).