It is to be noted that CD44 is not only one type of cancer stem cell markers19, but also functionally involved in cell-cell adhesion, even interlink extracellular matrixes with intracellular signaling networks 20, whilst, before the disseminated gastric cancer cells could form the peritoneal metastasis successfully, they must adhere to the peritoneal mesothelium tightly. Here, CD44 is linked to gastric cancer.