Based on high-quality ChIP-seq data in the Cistrome Data Browser 22 (http://cistrome.org/db/), miR-5188 was among the top putative miRNA targets of c-Jun identified as having a promoter region harboring binding sites for c-Jun in HCC, lung cancer, breast cancer and erythroleukemia (Figure 5A). The gene discussed is JUN; the disease is hepatocellular carcinoma.